Bioinformatics and Computational Biology

DEVELOPMENT OF STRUCTURAL INFORMATICS METHOD FOR BINDING PEPTIDES

Doctoral Candidate Name: John Patterson Program: Bioinformatics and Computational Biology Defense Date and Time: September 13, 2023 – 3:30 PM Defense Location: Room 301 in Bioinformatics building Committee chair’s Name: Dr. Donald Jacobs Committee Members: Dr. Anthony Fodor, Dr. Jun-tao Guo, Dr. Xiuxia Du, Dr. Michael Matthews Abstract: In the continuous pursuit of advanced therapeutics, […]

DE NOVO ASSEMBLIES OF GENOMES OF FOUR INDIGENOUS CHICKENS AND A WHITE EARED PHEASANT REVEAL GENETIC BASIS OF CHICKEN DOMESTICATION AND ALTITUDE ADAPTATION

Doctoral Candidate Name: Siwen Wu Program: Bioinformatics and Computational Biology Defense Date and Time: August 30, 2023 – 9:00 AM Defense Location: Bioinformatics building Room 105 Committee chair’s Name: Zhengchang Su Committee Members: Juntao Guo, Way Sung, Baohua Song Abstract: High-quality assembly and annotation of the genome of a species are critical in understanding the […]

Functional Dynamics in Beta-Lactamase: Insights into Substrate Recognition and Inhibition

Doctoral Candidate Name: Christopher Avery Program: Bioinformatics and Computational Biology Defense Date and Time: July 26, 2023 – 2:00 PM Defense Location: Bioinformatics Room 105 Committee chair’s Name: Dr Donald Jacobs Committee Members: Dr Jun-tao Guo, Dr Xiuxia Du, Dr Irina Nesmelova, Dr Jerry Troutman Abstract: Beta-lactamase proteins are major contributors to antibiotic resistance, rendering […]

Investigating Multidrug Resistance in Escherichia coli with Phylogenetics and Machine Learning

Doctoral Candidate Name: David C. Brown Program: Bioinformatics and Computational Biology Defense Date and Time: April 6, 2023 – 2:30 PM Defense Location: Bioinformatics Building, 4th Floor, Seminar Room Committee chair’s Name: Dr. Daniel Janies Committee Members: Dr. Jun-tao Guo, Dr. Alex Dornburg, Dr. Adam Reitzel Abstract: The next pandemic is already underway in the […]

Microbial Mutations – Accumulation in Microfluidics and Collateral Sensitivity

Doctoral Candidate Name: Nathan Tyler Turner Program: Bioinformatics and Computational Biology Defense Date and Time: April 3, 2023 – 12:00 PM Defense Location: Bioinformatics room 301 Committee chair’s Name: Way Sung Committee Members: Way Sung, Cynthia Gibas, Rebekah Rogers, Jun-tao Guo, Gang Chen Abstract: Mutations are a primary source of genetic variation and a major […]

Microbial Mutations – Accumulation in Microfluidics and Collateral Sensitivity

Doctoral Candidate Name: Nathan Tyler Turner Program: Bioinformatics and Computational Biology Defense Date and Time: April 3, 2023 – 12:00 PM Defense Location: Bioinformatics room 301 Committee chair’s Name: Way Sung Committee Members: Way Sung, Cynthia Gibas, Rebekah Rogers, Jun-tao Guo, Gang Chen Abstract: Mutations are a primary source of genetic variation and a major […]

ON COMPOSITIONALLY AWARE AND NAÏVE APPROACHES TO NORMALIZATION OF 16S MICROBIOME DATA

Doctoral Candidate Name: Aaron Yerke Program: Bioinformatics and Computational Biology Defense Date and Time: October 26, 2022 – 9:30 AM Defense Location: https://charlotte-edu.zoom.us/j/99052291735?pwd=RllLMDVtM0xpUVJyamJqNU92bW4wUT09 Committee chair’s Name: Dr. Anthony Fodor Committee Members: Dr. Elizabeth Cooper, Dr. ZhengChang Su, Dr. Alex Dornburg, Dr. Gabriel Terejanu Abstract: Compositional data refers to any data that represents parts of a […]

ON WHOLE GENOME CLASSIFIER PERFORMANCE IN RELATION TO 16S CLASSIFIERS

Doctoral Candidate Name: James Johnson Program: Bioinformatics and Computational Biology Defense Date and Time: September 30, 2022 – 10:00 AM Defense Location: Zoom: https://charlotte-edu.zoom.us/j/97413134504 Committee chair’s Name: Dr. Anthony Fodor Committee Members: Dr. Cynthia Gibas, Dr. Richard White, Dr. Alex Dornburg, Dr. Jacelyn Rice-Boayue, Dr. Todd Steck, Dr. Anthony Fodor Abstract: There is little consensus […]

Hydrogen bond energy-based comparative analysis of protein-ligand interactions and similarity assessment of protein-DNA complex models

Doctoral Candidate Name: Fareeha Kanwal Malik Program: Bioinformatics and Computational Biology Defense Date and Time: April 11, 2022 – 1:00 PM Defense Location: Virtual, please email me at fkanwal1@charlotte.edu for link Committee chair’s Name: Dr. Jun-tao Guo Committee Members: Dr. Jennifer Weller, Dr. Way Sung, Dr. Shan Yan Abstract: Hydrogen bonds play a vital role […]

NUTRITIVE KNOWLEDGE BASED DISCOVERY: ENHANCING PRECISION NUTRITION HYPOTHESIS GENERATION

Doctoral Candidate Name: Aaron Trautman Program: Bioinformatics and Computational Biology Defense Date and Time: April 5, 2022 – 1:00 PM Defense Location: https://uncc.zoom.us/j/99382586854?pwd=QUdKZjhNNUxlTDJZMUYraVhiNGI4QT09 Committee chair’s Name: Cory Brouwer Committee Members: Cynthia Gibas, Way Sung, Robert Reid Abstract: Diet-related diseases like obesity and type-2 diabetes are on the rise. Precision nu- trition, a way to tailor […]